Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | CDC25A | P30304 | 1/20 | 0.63 |
| ▸ | CDC25B | P30305 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30163040 | 0.97 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL23279 | 0.97 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL29899307 | 0.97 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL29350135 | 0.97 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL23861 | 0.97 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Bromide SCHEMBL1007533 | 0.95 | KDM4E (0.67) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Hydrochloric Acid SCHEMBL475975 | 0.95 | KDM4E (0.67) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL21328422 | 0.95 | KDM4E (0.67) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Ammonia Solution, Strong SCHEMBL2342923 | 0.95 | KDM4E (0.67) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL9679455 | 0.95 | KDM4E (0.67) | KDM4EHSD17B10CDC25ACDC25BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640008-B1 | THIN-FILM COMPOSITE MEMBRANE | FLUID SYS CORP (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5358745-A | Forming reaction product of n-alkyl phenylenediamine and polyacyl halide by interfacially applying on a porous support, post treated with acid, coated with polyvinyl alcohol and a buffer/or base to improve physical properties | FLUID SYSTEMS CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| US-5271843-A | Chlorine-tolerant, thin-film composite membrane | ALLIED-SIGNAL INC. (US) | 1993-12-21 | — | — | US | disclosed |
| US-5234598-A | Reaction product of an N-alkyl phenylenediamine and aromatic polyacyl chloride on support; interfacial polymerization; for desalination of water | ALLIED-SIGNAL INC. (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0489746-B1 | HIGH FLUX SEMIPERMEABLE MEMBRANES | AlliedSignal Inc. (US) | 1993-07-07 | — | — | EP | disclosed |
| EP-0489746-A1 | HIGH FLUX SEMIPERMEABLE MEMBRANES. | ALLIED SIGNAL INC (US) | 1992-06-17 | — | — | EP | disclosed |
| WO-1991003311-A1 | HIGH FLUX SEMIPERMEABLE MEMBRANES | ALLIED-SIGNAL INC. (US) | 1991-03-21 | — | — | WO | disclosed |
| US-4950404-A | REVERSE OSMOSIS; WATER DESLINATION | ALLIED-SIGNAL INC. (US) | 1990-08-21 | — | — | US | disclosed |