Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | CDC25A | P30304 | 1/20 | 0.63 |
| ▸ | CDC25B | P30305 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350135 | 0.97 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL23279 | 0.97 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL30163040 | 0.97 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL29899307 | 0.97 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL23861 | 0.97 | KDM4E (0.69) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Iodide SCHEMBL9015466 | 0.95 | KDM4E (0.67) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Hydrochloric Acid SCHEMBL475975 | 0.95 | KDM4E (0.67) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL21328422 | 0.95 | KDM4E (0.67) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| SCHEMBL9679455 | 0.95 | KDM4E (0.67) | KDM4EHSD17B10CDC25ACDC25BPOLB | |
| Ammonia Solution, Strong SCHEMBL2342923 | 0.95 | KDM4E (0.67) | KDM4EHSD17B10CDC25ACDC25BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101980997-B | Process for production of high-purity trimellitic acid | MITSUBISHI GAS CHEMICAL CO | 2013-08-21 | — | — | CN | disclosed |
| US-20110112323-A1 | PROCESS FOR PRODUCTION OF HIGH-PURITY TRIMELLITIC ACID | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2011-05-12 | — | — | US | disclosed |
| CN-101980997-A | Process for production of high-purity trimellitic acid | MITSUBISHI GAS CHEMICAL CO | 2011-02-23 | — | — | CN | disclosed |
| EP-2269973-A1 | PROCESS FOR PRODUCTION OF HIGH-PURITY TRIMELLITIC ACID | Mitsubishi Gas Chemical Company, Inc. (JP) | 2011-01-05 | — | — | EP | disclosed |
| EP-0640008-B1 | THIN-FILM COMPOSITE MEMBRANE | FLUID SYS CORP (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5358745-A | Forming reaction product of n-alkyl phenylenediamine and polyacyl halide by interfacially applying on a porous support, post treated with acid, coated with polyvinyl alcohol and a buffer/or base to improve physical properties | FLUID SYSTEMS CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| US-5271843-A | Chlorine-tolerant, thin-film composite membrane | ALLIED-SIGNAL INC. (US) | 1993-12-21 | — | — | US | disclosed |
| US-4950404-A | REVERSE OSMOSIS; WATER DESLINATION | ALLIED-SIGNAL INC. (US) | 1990-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112323-A1 | PROCESS FOR PRODUCTION OF HIGH-PURITY TRIMELLITIC ACID | TRIM4, TRIM58, TRIM28 | KDM4E 413/4885HSD17B10 757/4885CDC25A 2393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.