Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.74 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015398 | 0.89 | TBXAS1 (0.80) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL9015400 | 0.89 | TBXAS1 (0.80) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL9255021 | 0.87 | TBXAS1 (0.74) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL9015436 | 0.83 | TBXAS1 (1.00) | TBXAS1TBXA2R | |
| SCHEMBL7776190 | 0.81 | TBXAS1 (0.52) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL9256574 | 0.81 | TBXAS1 (0.84) | TBXAS1TBXA2R | |
| SCHEMBL9015475 | 0.77 | TBXA2R (0.52) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL9015416 | 0.77 | HDAC8 (0.52) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL8105704 | 0.76 | TBXA2R (0.48) | TBXAS1TBXA2RHDAC8 | |
| SCHEMBL9255907 | 0.75 | TBXAS1 (1.00) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648741-B1 | 1,2,3,4-Tetrahydronaphthalene, chroman and thiochroman derivatives as antithrombotic agents | ADIR (FR) | 1996-12-18 | — | — | EP | disclosed |
| US-5472979-A | Antithrombotics | ADIR ET COMPAGNIE (FR) | 1995-12-05 | — | — | US | disclosed |
| EP-0648741-A1 | 1,2,3,4-Tetrahydronaphthalene, chroman and thiochroman derivatives as antithrombotic agents | ADIR ET COMPAGNIE (FR) | 1995-04-19 | — | — | EP | disclosed |