Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28886383 | 0.93 | TDP1 (0.59) | TDP1EGFRHDAC3LMNAALDH1A1 | |
| SCHEMBL119066 | 0.89 | TDP1 (0.55) | TDP1EGFRHDAC3LMNAALDH1A1 | |
| SCHEMBL28378630 | 0.84 | TDP1 (0.67) | TDP1EGFRHDAC3LMNAALDH1A1 | |
| SCHEMBL5667176 | 0.84 | TDP1 (0.52) | TDP1EGFRHDAC3LMNAALDH1A1 | |
| SCHEMBL5667169 | 0.84 | TDP1 (0.52) | TDP1EGFRHDAC3LMNAALDH1A1 | |
| SCHEMBL23702410 | 0.80 | BCHE (0.50) | TDP1EGFRHDAC3LMNAAKR1B10 | |
| SCHEMBL23702408 | 0.80 | BCHE (0.50) | TDP1EGFRHDAC3LMNAAKR1B10 | |
| SCHEMBL483427 | 0.80 | TDP1 (0.76) | TDP1EGFRHDAC3LMNAALDH1A1 | |
| SCHEMBL483426 | 0.80 | TDP1 (0.76) | TDP1EGFRHDAC3LMNAALDH1A1 | |
| SCHEMBL28188071 | 0.79 | TDP1 (0.74) | TDP1EGFRHDAC3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589165-A | CONTAINING AN ORGANOFLUORINATED MODIFIED SILICONE RESIN | SHISEIDO CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |