SCHEMBL119066

SCHEMBL119066

CCCCCC(CC)COOC(=O)C=Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.55
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
ALDH1A1 P00352 3/20 0.46
CA2 P00918 1/20 0.46
CYP3A4 P08684 1/20 0.46
EGFR P00533 1/20 0.45
LMNA P02545 4/20 0.43
MAPK1 P28482 1/20 0.43
HDAC3 O15379 1/20 0.42
TSHR P16473 1/20 0.40
AKR1B10 O60218 1/20 0.39
AKR1B1 P15121 1/20 0.39
TUBB4A P04350 2/20 0.39
TUBB P07437 2/20 0.39
TUBA3C P0DPH7 2/20 0.39
TUBA1B P68363 2/20 0.39
TUBA4A P68366 2/20 0.39
TUBB4B P68371 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28886383 0.96 TDP1 (0.59) TDP1PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL9015711 0.89 TDP1 (0.50) TDP1ALDH1A1CA2CYP3A4EGFR
SCHEMBL5667169 0.85 TDP1 (0.52) TDP1PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL5667176 0.85 TDP1 (0.52) TDP1PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL483427 0.84 TDP1 (0.76) TDP1PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL483426 0.84 TDP1 (0.76) TDP1PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL28188071 0.82 TDP1 (0.74) TDP1PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL28474356 0.80 EGFR (0.47) TDP1ALDH1A1EGFRLMNAHDAC3
SCHEMBL28677409 0.80 EGFR (0.47) TDP1ALDH1A1EGFRLMNAHDAC3
SCHEMBL32076 0.79 EGFR (0.55) EGFRLMNAHDAC3AKR1B10AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251125-A1 COMPOSITIONS AND METHODS FOR PREVENTING AND PROTECTING AGAINST DAMAGE IN CELLS AND TISSUES F3 Platform Biologics, Inc. (US) 2023-10-04 EP claimed
US-20230000735-A1 ANTI-WRINKLE COSMETIC COMPOSITION, COMPOSITION SYSTEM AND METHOD FOR COSMETIC SKIN TREATMENT Natura Cosméticos S.A. (BR) 2023-01-05 US claimed
US-11478409-B2 Anti-wrinkle cosmetic composition, composition system and method for cosmetic skin treatment NATURA COSMETICOS S.A. (BR) 2022-10-25 US claimed
WO-2022115360-A1 COMPOSITIONS AND METHODS FOR PREVENTING AND PROTECTING AGAINST DAMAGE IN CELLS AND TISSUES F3 PLATFORM BIOLOGICS, INC. (US) 2022-06-02 WO claimed
US-20200113795-A1 COSMETIC COMPOSITION AND PREPARATION METHOD THEREFOR AMOREPACIFIC CORPORATION (KR) 2020-04-16 US claimed
US-20190167540-A1 ANTI-WRINKLE COSMETIC COMPOSITION, COMPOSITION SYSTEM AND METHOD FOR COSMETIC SKIN TREATMENT Natura Cosméticos S.A. (BR) 2019-06-06 US claimed
EP-3466406-A1 ANTI-WRINKLE COSMETIC COMPOSITION, COMPOSITION SYSTEM AND METHOD FOR COSMETIC SKIN TREATMENT Natura Cosméticos S.A. (BR) 2019-04-10 EP claimed
US-8152860-B2 Cosmetic composition for coloring hair comprising a direct hair dye and a carrier system comprising polysaccharides ROVI COSMETICS INTERNATIONAL GMBH (DE) 2012-04-10 US claimed
WO-2009069933-A2 OIL-IN-WATER SOLID COSMETIC COMPOSITION WITH HIGHER STABILITY AGAINST EVAPORATION OF INTERNAL PHASE (WATER) AS WELL AS OUTSTANDING MOISTURIZING EFFECT AMOREPACIFIC CORPORATION (KR) 2009-06-04 WO claimed
EP-2040667-A1 MOISTURISING AND SUNSCREEN SKINCARE COMPOSITION Reckitt & Colman (Overseas) Limited (GB) 2009-04-01 EP claimed
WO-2007144670-A1 MOISTURISING AND SUNSCREEN SKINCARE COMPOSITION RECKITT & COLMAN (OVERSEAS) LIMITED (GB) 2007-12-21 WO claimed
US-7208142-B2 Indanylidene compounds SYMRISE GMBH & CO. KG (DE) 2007-04-24 US claimed
US-7147841-B2 Formulation of UV absorbers by incorporation in solid lipid nanoparticles CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-12-12 US claimed
EP-1378231-A1 Formulation of UV absorbers by incorporation in solid lipid nanoparticles Ciba Specialty Chemicals Holding Inc. (CH) 2004-01-07 EP claimed
US-20030235540-A1 Formulation of UV absorbers by incorporation in solid lipid nanoparticles CIBA SPECIALTY CHEMICALS CORP. 2003-12-25 US claimed
US-20020143203-A1 Novel indanylidene compounds SYMRISE GMBH & CO. KG (DE) 2002-10-03 US claimed
EP-3698770-B1 COSMETIC COMPOSITION FOR BLOCKING FINE DUST LG HOUSEHOLD & HEALTH CARE LTD (KR) 2024-09-11 EP disclosed
US-20240122948-A1 COMPOSITIONS AND METHODS FOR PREVENTING AND PROTECTING AGAINST DAMAGE IN CELLS AND TISSUES F3 PLATFORM BIOLOGICS, INC. 2024-04-18 US disclosed
WO-1999051220-A1 METHODS AND COMPOSITIONS FOR REDUCING UV-INDUCED INHIBITION OF COLLAGEN SYNTHESIS IN HUMAN SKIN THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1999-10-14 WO disclosed
WO-1998055075-A2 COMPOSITIONS AND METHODS FOR INHIBITING PHOTOAGING OF SKIN REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1998-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030235540-A1 Formulation of UV absorbers by incorporation in solid lipid nanoparticles CUTA, LIPC, AUP1 TDP1 3276/4885PRSS1 1359/4885PRSS2 1533/4885
US-20020143203-A1 Novel indanylidene compounds CUTA, NISCH, ERCC4 TDP1 3816/4885PRSS1 3624/4885PRSS2 3362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.