Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | IAPP | P10997 | 5/20 | 0.42 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL8099142 | 0.88 | KDM4E (0.59) | ALDH1A1KDM4EHPGDMAPTHTT | |
| Phthalic Acid SCHEMBL48951 | 0.84 | TSHR (0.44) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| Phthalic Acid SCHEMBL10748199 | 0.79 | TSHR (0.46) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL10388912 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDALOX5TERT | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL19953770 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDALOX5TERT | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL30940445 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDALOX5TERT | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL2831364 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDALOX5TERT | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL2033960 | 0.78 | KDM4E (0.68) | ALDH1A1KDM4EHPGDALOX5TERT | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL3980948 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDALOX5TERT | |
| 2,3-Dihydroxybenzoic Acid SCHEMBL31148351 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDALOX5TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583157-A | ANTICARCINOGENIC AND ANTITUMOR AGENTS | PHARMACHEMIE B.V. (NL) | 1996-12-10 | — | — | US | claimed |
| US-5583157-A | ANTICARCINOGENIC AND ANTITUMOR AGENTS | PHARMACHEMIE B.V. (NL) | 1996-12-10 | — | — | US | disclosed |
| EP-0677528-A1 | Dibutyltin bis(dihydroxybenzoates) and compositions containing these compounds | PHARMACHEMIE B.V. (NL) | 1995-10-18 | — | — | EP | disclosed |
| EP-0677528-A1 | Dibutyltin bis(dihydroxybenzoates) and compositions containing these compounds | PHARMACHEMIE B.V. (NL) | 1995-10-18 | — | — | EP | disclosed |