Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 4/20 | 0.63 |
| ▸ | GSK3B | P49841 | 4/20 | 0.57 |
| ▸ | COMT | P21964 | 1/20 | 0.57 |
| ▸ | MRE11 | P49959 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9015993 | 1.00 | XDH (0.63) | XDHGSK3BCOMTMRE11MEN1 | |
| SCHEMBL8049588 | 0.87 | GSK3B (0.74) | XDHGSK3BCOMTHPGD | |
| SCHEMBL8049587 | 0.87 | GSK3B (0.74) | XDHGSK3BCOMTHPGD | |
| SCHEMBL6419329 | 0.85 | GSK3B (0.79) | XDHGSK3BMRE11MEN1KMT2A | |
| SCHEMBL8038859 | 0.85 | GSK3B (0.74) | XDHGSK3BCOMTMEN1KMT2A | |
| SCHEMBL6413941 | 0.85 | XDH (0.70) | XDHGSK3BMRE11MEN1KMT2A | |
| SCHEMBL8038857 | 0.85 | GSK3B (0.74) | XDHGSK3BCOMTMEN1KMT2A | |
| SCHEMBL6419332 | 0.85 | GSK3B (0.79) | XDHGSK3BMRE11MEN1KMT2A | |
| SCHEMBL6413936 | 0.85 | XDH (0.70) | XDHGSK3BMRE11MEN1KMT2A | |
| SCHEMBL8051036 | 0.78 | TDP1 (0.59) | XDHGSK3BCOMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526598-B1 | NEW PHARMACOLOGICALLY ACTIVE CATECHOL DERIVATIVES | ORION YHTYMAE OY (FI) | 1996-12-18 | — | — | EP | disclosed |