SCHEMBL9016192

SCHEMBL9016192

CC/C=C/COc1ccc(-c2ccc(-c3ccc(C4CCC(C)CC4)c(F)c3F)cc2)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 3/20 0.33
FEN1 P39748 3/20 0.33
FPR2 P25090 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13000257 0.97 ALOX5AP (0.31) ALOX5APFEN1FPR2
SCHEMBL8934839 0.91 PTGDR (0.30) ALOX5APFEN1
SCHEMBL8934980 0.86 HTR2C (0.37) ALOX5APFEN1
SCHEMBL12999899 0.85 FEN1 (0.36) ALOX5APFEN1FPR2
SCHEMBL8935905 0.85 GAA (0.32)
SCHEMBL19985583 0.84 ALOX5AP (0.32) ALOX5APFEN1
SCHEMBL13000032 0.84 FPR2 (0.35) ALOX5APFEN1FPR2
SCHEMBL8962031 0.83 HTR2C (0.35) ALOX5APFEN1
SCHEMBL8952802 0.83 FPR2 (0.31) FPR2
SCHEMBL8963415 0.82 GAA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
EP-2206695-A1 TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2010-07-14 EP disclosed