SCHEMBL9016196

SCHEMBL9016196

CC1=C(C/C=C(C)/C=C/C(=O)O)C(C)(C)CCC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.51
RXRA P19793 8/20 0.44
RARB P10826 7/20 0.44
RARG P13631 7/20 0.44
ALDH1A1 P00352 7/20 0.44
MAPT P10636 7/20 0.44
RARA P10276 6/20 0.44
CYP3A4 P08684 4/20 0.44
RXRB P28702 4/20 0.44
RXRG P48443 4/20 0.44
PTGS1 P23219 3/20 0.44
MAPK1 P28482 3/20 0.44
RORC P51449 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
HTR2B P41595 2/20 0.44
BLM P54132 2/20 0.44
HIF1A Q16665 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MEN1 O00255 2/20 0.44
APP P05067 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016198 1.00 CYP1A2 (0.51) CYP1A2RXRARARBRARGALDH1A1
SCHEMBL26967412 0.90 ALDH1A1 (0.43) CYP1A2RXRARARBRARGALDH1A1
SCHEMBL9737637 0.85 ALDH1A1 (0.42) CYP1A2RXRARARBRARGALDH1A1
SCHEMBL9737640 0.85 ALDH1A1 (0.42) CYP1A2RXRARARBRARGALDH1A1
SCHEMBL9182001 0.83 ALDH1A1 (0.49) CYP1A2RXRARARBRARGALDH1A1
SCHEMBL9187020 0.83 ALDH1A1 (0.49) CYP1A2RXRARARBRARGALDH1A1
SCHEMBL9209859 0.83 ALDH1A1 (0.49) CYP1A2RXRARARBRARGALDH1A1
SCHEMBL113634 0.82 RARB (0.41) CYP1A2RXRARARBRARGALDH1A1
SCHEMBL110933 0.82 RARB (0.41) CYP1A2RXRARARBRARGALDH1A1
SCHEMBL2706978 0.82 CYP1A2 (0.56) CYP1A2RXRARARBRARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403945-B1 Cycloaliphatic carbinols and their use as starting materials for the preparation of furan derivatives FIRMENICH & CIE (CH) 1996-12-18 EP disclosed
EP-0403945-A2 Cycloaliphatic carbinols and their use as starting materials for the preparation of furan derivatives FIRMENICH SA (CH) 1990-12-27 EP disclosed