Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016215 | 0.82 | MEN1 (0.61) | KMT2AMEN1KDM4E | |
| SCHEMBL9016247 | 0.78 | POLB (0.49) | HTR2BKCNH2KMT2AMEN1 | |
| SCHEMBL7310315 | 0.77 | KMT2A (0.66) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL7317219 | 0.76 | ADRB2 (0.63) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL11153245 | 0.76 | KMT2A (0.64) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL7310430 | 0.76 | ADRB2 (0.55) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL11787642 | 0.76 | ADRB2 (0.63) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL11884643 | 0.74 | ADRB2 (0.80) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL11668773 | 0.74 | ADRB2 (0.69) | ADRB2ADRB1HTR1AADRA2CSLC6A4 | |
| SCHEMBL7310568 | 0.74 | KMT2A (0.70) | ADRB2ADRB1HTR1AADRA2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482964-A | ANTIEPILEPTIC | WARNER-LAMBERT COMPANY (US) | 1996-01-09 | — | — | US | disclosed |