Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | CKS1B | P61024 | 2/20 | 0.46 |
| ▸ | SKP1 | P63208 | 2/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27432362 | 0.79 | MAPT (0.42) | KITTLR9TLR7SLC2A1KMT2A | |
| SCHEMBL8700308 | 0.76 | PTPN11 (0.48) | KITCKS1BSKP1SKP2TLR9 | |
| SCHEMBL6964672 | 0.76 | KIT (0.44) | KITCKS1BSKP1SKP2TLR9 | |
| SCHEMBL8699714 | 0.71 | MAPT (0.50) | TLR9TLR7 | |
| SCHEMBL7981893 | 0.71 | GAA (0.56) | CKS1BSKP1SKP2ACHESMARCA2 | |
| SCHEMBL24951551 | 0.70 | GBA1 (0.56) | KITCKS1BSKP1SKP2ACHE | |
| SCHEMBL7626374 | 0.70 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL30819461 | 0.70 | GBA1 (0.56) | KITCKS1BSKP1SKP2ACHE | |
| SCHEMBL2366187 | 0.70 | GBA1 (0.47) | KITCKS1BSKP1SKP2TLR9 | |
| SCHEMBL24970896 | 0.70 | GBA1 (0.53) | KITCKS1BSKP1SKP2TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |