Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 2/20 | 0.44 |
| ▸ | SKP1 | P63208 | 2/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.44 |
| ▸ | GBA1 | P04062 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964672 | 0.84 | KIT (0.44) | PTPN11KITCKS1BSKP1SKP2 | |
| SCHEMBL8699207 | 0.83 | GAA (0.41) | ACHEMAPTALDH1A1HTTMEN1 | |
| SCHEMBL9016294 | 0.76 | KIT (0.46) | PTPN11KITCKS1BSKP1SKP2 | |
| SCHEMBL8699714 | 0.76 | MAPT (0.50) | TLR9TLR7MAPTALDH1A1LMNA | |
| SCHEMBL6955265 | 0.75 | GBA1 (0.48) | PTPN11KITCKS1BSKP1SKP2 | |
| SCHEMBL8699373 | 0.72 | MAPT (0.47) | NAMPTMAPTALDH1A1HTTMEN1 | |
| SCHEMBL6956245 | 0.72 | NAMPT (0.42) | KITNAMPTTLR9MAPTSMN1; SMN2 | |
| SCHEMBL6965376 | 0.71 | MAPT (0.44) | NAMPTTLR9TLR7MAPTSMN1; SMN2 | |
| SCHEMBL6942730 | 0.71 | GAA (0.69) | PTPN11NAMPTMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL31652099 | 0.70 | TLR9 (0.54) | KITCKS1BSKP1SKP2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |