Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016367 | 0.79 | TYMP (0.31) | TYMP | |
| SCHEMBL7540892 | 0.66 | TYMP (0.70) | TYMP | |
| SCHEMBL14423060 | 0.64 | TYMP (0.47) | TYMPALDH1A1CYP1A2CYP2C19PDE3B | |
| SCHEMBL17551856 | 0.62 | MAPT (0.50) | TYMPALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL9354404 | 0.59 | TYMP (0.37) | TYMPALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL11762589 | 0.58 | DHODH (0.55) | CYP1A2CYP2C19 | |
| SCHEMBL18884210 | 0.58 | KDM4E (0.50) | TYMPALDH1A1MAPTPDE3BPDE3A | |
| SCHEMBL27906010 | 0.56 | TSHR (0.36) | TYMPALDH1A1 | |
| SCHEMBL20799748 | 0.55 | TYMP (0.50) | TYMP | |
| SCHEMBL9592776 | 0.55 | TYMP (0.46) | TYMPALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748316-A1 | PYRIMIDINE ACYCLONUCLEOSIDE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1996-12-18 | — | — | EP | disclosed |