SCHEMBL9016483

SCHEMBL9016483

CON=CCC(Oc1ccccc1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.50
PPARA Q07869 17/20 0.50
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016409 0.83 PPARG (0.54) PPARGPPARA
SCHEMBL28442511 0.77 PPARG (0.54) PPARGPPARA
SCHEMBL585488 0.76 PPARG (0.53) PPARGPPARA
SCHEMBL17724342 0.74 PPARG (0.59) PPARGPPARA
SCHEMBL8358395 0.73 PPARG (0.46) PPARGPPARA
SCHEMBL4651839 0.73 SMN1; SMN2 (0.64) PPARGPPARAALDH1A1
SCHEMBL295888 0.73 SMN1; SMN2 (0.64) PPARGPPARAALDH1A1
SCHEMBL5512522 0.73 PPARG (0.57) PPARGPPARA
SCHEMBL9016500 0.73 PPARG (0.41) PPARGPPARAALDH1A1LMNANPC1
SCHEMBL9016505 0.73 PPARG (0.41) PPARGPPARAALDH1A1LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5574153-A BACTERICIDES ACS DOBFAR S.P.A. (IT) 1996-11-12 US disclosed
EP-0638574-A1 Oxime derivatives of cephalosporanic structure and compounds for their preparation ACS DOBFAR S.p.A. (IT) 1995-02-15 EP disclosed