Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016500 | 1.00 | PPARG (0.41) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL9016470 | 0.86 | CYP3A4 (0.44) | NPC1POLBMAPTRAB9AKMT2A | |
| SCHEMBL9016461 | 0.86 | PPARG (0.36) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL9016513 | 0.83 | ADAMTS4 (0.37) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL9016432 | 0.81 | MEN1 (0.44) | GAAALDH1A1LMNANPC1HTT | |
| SCHEMBL9016533 | 0.81 | MEN1 (0.46) | CYP1A2ALDH1A1LMNANPC1POLB | |
| SCHEMBL354834 | 0.74 | CYP1A2 (0.43) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL4582830 | 0.74 | GAA (0.43) | PPARGPPARACYP1A2GAACYP2C9 | |
| SCHEMBL9016483 | 0.73 | PPARG (0.50) | PPARGPPARAALDH1A1LMNANPC1 | |
| SCHEMBL5556068 | 0.73 | CYP2C19 (0.42) | PPARGPPARACYP1A2GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5574153-A | BACTERICIDES | ACS DOBFAR S.P.A. (IT) | 1996-11-12 | — | — | US | disclosed |
| EP-0638574-A1 | Oxime derivatives of cephalosporanic structure and compounds for their preparation | ACS DOBFAR S.p.A. (IT) | 1995-02-15 | — | — | EP | disclosed |