⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637824 | 0.74 | — | — | |
| SCHEMBL8655068 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL15034720 | 0.57 | MAPT (0.54) | — | |
| SCHEMBL11443292 | 0.56 | — | — | |
| SCHEMBL11641704 | 0.55 | CYP1A2 (0.50) | — | |
| SCHEMBL24156967 | 0.53 | MAPT (0.34) | — | |
| SCHEMBL11527821 | 0.53 | MAPT (0.34) | — | |
| SCHEMBL8779829 | 0.53 | CCR1 (0.39) | — | |
| SCHEMBL11466443 | 0.52 | — | — | |
| SCHEMBL9089789 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748315-A1 | USE OF IMIDAZOLE DERIVATIVES FOR TREATING DISORDERS INVOLVING ANGIOTENSIN RECEPTORS AT 1? AND AT 2?, CERTAIN SUCH PRODUCTS, PREPARATION THEREOF, USE THEREOF AS DRUGS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | ROUSSEL UCLAF (FR) | 1996-12-18 | — | — | EP | disclosed |