Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397336 | 0.81 | ATM (0.52) | ATMCYP2C9MAOAMAOBHDAC3 | |
| SCHEMBL9242929 | 0.79 | GRM2 (0.56) | ATMCYP2C9MAOAMAOBHDAC3 | |
| SCHEMBL29591768 | 0.79 | CYP2C9 (0.49) | ATMCYP2C9MAOAMAOBHDAC3 | |
| SCHEMBL9091772 | 0.79 | CYP2C9 (0.49) | ATMCYP2C9MAOAMAOBHDAC3 | |
| Hydrochloric Acid SCHEMBL9240770 | 0.77 | GRM2 (0.55) | ATMCYP2C9MAOAMAOBHDAC3 | |
| SCHEMBL262699 | 0.77 | CYP2C9 (0.47) | ATMCYP2C9MAOAMAOBHDAC3 | |
| Hydrochloric Acid SCHEMBL9247358 | 0.77 | GRM2 (0.55) | ATMCYP2C9MAOAMAOBHDAC3 | |
| SCHEMBL11793574 | 0.75 | L3MBTL1 (0.51) | ATMCYP2C9MAOAMAOBHDAC3 | |
| SCHEMBL30497767 | 0.75 | TSHR (0.69) | ATMCYP2C9MAOAMAOBHDAC3 | |
| SCHEMBL3418964 | 0.71 | PPARG (0.49) | ATMCYP2C9LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571825-A | Method of selectively inhibiting prostaglandin G/H synthase-2 | WARNER-LAMBERT COMPANY (US) | 1996-11-05 | — | — | US | disclosed |