Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.64 |
| ▸ | THRA | P10827 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | RARB | P10826 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | RARA | P10276 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380722 | 1.00 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL8357893 | 1.00 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL9514956 | 1.00 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL11135663 | 1.00 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL8375690 | 1.00 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL9341873 | 1.00 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL9342490 | 1.00 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL9571636 | 1.00 | THRB (0.64) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL8021213 | 0.98 | THRB (0.62) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL9511143 | 0.98 | THRB (0.62) | THRBTHRAMAPTSMN1; SMN2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1582506-A | Substituted pentacene semiconductors | 3M INNOVATIVE PROPERTIES CO (US) | 2005-02-16 | — | — | CN | disclosed |
| EP-0453010-B1 | Copolymer compositions comprising a copolymer and one or more lubricating additives | SHELL INT RESEARCH (NL) | 1996-06-05 | — | — | EP | disclosed |
| EP-0453010-A1 | Copolymer compositions comprising a copolymer and one or more lubricating additives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-10-23 | — | — | EP | disclosed |