SCHEMBL9016858

SCHEMBL9016858

CCCCCCCCCCCCCCCCCCCCCCCCCCCCOc1ccc(C(C)(C)c2ccc(OCCCCCCCCCCCCCCCCCCCCCCCCCCCC)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.61
LTA4H P09960 4/20 0.55
TP53 P04637 2/20 0.54
TSHR P16473 1/20 0.54
PLA2G4B P0C869 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
RARB P10826 3/20 0.50
PSMB1 P20618 1/20 0.50
PSMB5 P28074 1/20 0.50
PSMB2 P49721 1/20 0.50
NPC1 O15118 1/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
RAB9A P51151 1/20 0.50
HSD17B10 Q99714 1/20 0.50
S1PR1 P21453 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13227405 1.00 NR5A1 (0.61) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL10013798 1.00 NR5A1 (0.61) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL4738149 0.94 SMN1; SMN2 (0.58) NR5A1LTA4HTP53TSHRSMN1; SMN2
SCHEMBL9394712 0.90 NR5A1 (0.74) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL23266158 0.89 NR5A1 (0.61) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL13216578 0.89 NR5A1 (0.61) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL8727734 0.89 NR5A1 (0.61) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL12762363 0.89 NR5A1 (0.61) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL12251286 0.89 NR5A1 (0.61) NR5A1LTA4HTP53TSHRPLA2G4B
SCHEMBL14452733 0.87 NR5A1 (0.49) NR5A1LTA4HTP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0453010-B1 Copolymer compositions comprising a copolymer and one or more lubricating additives SHELL INT RESEARCH (NL) 1996-06-05 EP claimed
EP-0453010-A1 Copolymer compositions comprising a copolymer and one or more lubricating additives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-10-23 EP claimed
EP-0453010-B1 Copolymer compositions comprising a copolymer and one or more lubricating additives SHELL INT RESEARCH (NL) 1996-06-05 EP disclosed
EP-0453010-A1 Copolymer compositions comprising a copolymer and one or more lubricating additives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-10-23 EP disclosed