SCHEMBL4738149

SCHEMBL4738149

CCCCOc1ccc(C(C)(C)c2ccc(OCCCC)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.58
PSMB1 P20618 1/20 0.54
PSMB5 P28074 1/20 0.54
PSMB2 P49721 1/20 0.54
LTA4H P09960 4/20 0.53
NR5A1 Q13285 1/20 0.52
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
HTT P42858 2/20 0.51
TSHR P16473 3/20 0.50
TP53 P04637 2/20 0.50
MAPT P10636 2/20 0.50
HPGD P15428 2/20 0.50
HIF1A Q16665 2/20 0.50
CYP1A2 P05177 1/20 0.50
PPARG P37231 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9016858 0.94 NR5A1 (0.61) SMN1; SMN2PSMB1PSMB5PSMB2LTA4H
SCHEMBL10013798 0.94 NR5A1 (0.61) SMN1; SMN2PSMB1PSMB5PSMB2LTA4H
SCHEMBL13227405 0.94 NR5A1 (0.61) SMN1; SMN2PSMB1PSMB5PSMB2LTA4H
SCHEMBL14962790 0.92 SMN1; SMN2 (0.51) SMN1; SMN2PSMB1PSMB5PSMB2LTA4H
SCHEMBL12458332 0.92 SMN1; SMN2 (0.51) SMN1; SMN2PSMB1PSMB5PSMB2LTA4H
SCHEMBL15431171 0.92 SMN1; SMN2 (0.51) SMN1; SMN2PSMB1PSMB5PSMB2LTA4H
SCHEMBL84118 0.91 SMN1; SMN2 (0.58) SMN1; SMN2PSMB1PSMB5PSMB2LTA4H
SCHEMBL13567687 0.91 LTA4H (0.68) SMN1; SMN2PSMB1PSMB5PSMB2LTA4H
SCHEMBL19978962 0.91 KDM4E (0.52) SMN1; SMN2PSMB1PSMB5PSMB2LTA4H
SCHEMBL24900696 0.88 SMN1; SMN2 (0.47) SMN1; SMN2PSMB1PSMB5PSMB2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11460774-B2 Photosensitive resin composition, photosensitive dry film, and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-10-04 US disclosed
US-20200201182-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE DRY FILM, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-06-25 US disclosed
US-9567501-B2 Silicone pressure-sensitive adhesive composition having improved substrate adhesion and pressure-sensitive adhesive article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-14 US disclosed
US-20150240141-A1 SILICONE PRESSURE-SENSITIVE ADHESIVE COMPOSITION HAVING IMPROVED SUBSTRATE ADHESION AND PRESSURE-SENSITIVE ADHESIVE ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-27 US disclosed
US-8378340-B2 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-19 US disclosed
US-8222426-B2 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-17 US disclosed
US-20120123051-A1 ADHESIVE SILICONE RUBBER COMPOSITION WACKER CHEMIE AG (DE) 2012-05-17 US disclosed
US-7842941-B2 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-30 US disclosed
US-20100256396-A1 AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-07 US disclosed
US-20070063190-A1 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed
US-20070063190-A1 Aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256396-A1 AROMATIC COMPOUND AHR, AR, NR0B1 SMN1; SMN2 4256/4885PSMB1 608/4885PSMB5 237/4885
US-20070063190-A1 Aromatic compound AHR, AR, NR0B1 SMN1; SMN2 4243/4885PSMB1 565/4885PSMB5 216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.