Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 3/20 | 0.32 |
| ▸ | ATP4B | P51164 | 3/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698389 | 1.00 | MAPT (0.35) | MAPTALDH1A1TP53MAPK1CYP1A2 | |
| SCHEMBL8698387 | 1.00 | MAPT (0.35) | MAPTALDH1A1TP53MAPK1CYP1A2 | |
| SCHEMBL8698048 | 0.83 | MAPT (0.37) | MAPTALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL8698052 | 0.83 | MAPT (0.37) | MAPTALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL8707525 | 0.79 | MAPT (0.31) | MAPT | |
| SCHEMBL8701780 | 0.79 | MAPT (0.31) | MAPT | |
| SCHEMBL9016906 | 0.71 | MAPT (0.50) | MAPTALDH1A1TP53MAPK1CYP1A2 | |
| SCHEMBL9016864 | 0.71 | DRD2 (0.50) | DRD2DRD3 | |
| SCHEMBL9016879 | 0.71 | DRD2 (0.50) | DRD2DRD3 | |
| SCHEMBL14428964 | 0.67 | CYP3A4 (0.50) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541198-A | ANTISTICKING AGENTS FOR PLATELETS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-30 | — | — | US | disclosed |
| EP-0651747-B1 | CARBOSTYRYL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| EP-0651747-A1 | CARBOSTYRIL DERIVATIVES. | OTSUKA PHARMA CO LTD (JP) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994026732-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-24 | — | — | WO | disclosed |