Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27338847 | 0.83 | — | — | |
| SCHEMBL30342933 | 0.78 | CYP1A2 (0.42) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL29995615 | 0.77 | CYP1A2 (0.41) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL11000961 | 0.77 | CYP1A2 (0.41) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL11133777 | 0.77 | CYP1A2 (0.41) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL13069213 | 0.76 | CA1 (0.33) | — | |
| SCHEMBL8791144 | 0.74 | EPHX1 (0.44) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL24389250 | 0.73 | CA1 (0.35) | CYP1A2 | |
| SCHEMBL29385123 | 0.72 | EPHX1 (0.48) | S1PR2S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL29559353 | 0.72 | EPHX1 (0.48) | S1PR2S1PR4S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543530-A | 4-arylisoindole analgesics | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-08-06 | — | — | US | disclosed |