Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948200 | 0.80 | CYP1A2 (0.33) | CYP1A2CYP2D6 | |
| SCHEMBL19434115 | 0.77 | CA1 (0.46) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL13069213 | 0.76 | CA1 (0.33) | CA1CA2CA4 | |
| SCHEMBL5547886 | 0.75 | CA1 (0.50) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL9016919 | 0.73 | S1PR2 (0.32) | CYP1A2 | |
| SCHEMBL9637783 | 0.71 | CA1 (0.45) | CA1CA2CA4CYP1A2CYP2D6 | |
| SCHEMBL15259458 | 0.71 | CA1 (0.36) | CA1CA2CA4 | |
| SCHEMBL24751783 | 0.71 | GBA1 (0.41) | — | |
| SCHEMBL17121782 | 0.69 | CCR5 (0.36) | HTR2C | |
| SCHEMBL15745409 | 0.68 | CA1 (0.34) | CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238968-A1 | INDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022088551-A1 | INDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海领泰生物医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |