Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | CCL2 | P13500 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28131615 | 0.76 | BRD4 (0.42) | BRD4CCL2CYP3A4MAOALMNA | |
| SCHEMBL7032000 | 0.76 | BRD4 (0.42) | BRD4CCL2CYP3A4MAOALMNA | |
| SCHEMBL28130908 | 0.76 | BRD4 (0.42) | BRD4CCL2CYP3A4MAOALMNA | |
| Hydrochloric Acid SCHEMBL9016936 | 0.74 | BRD4 (0.41) | BRD4CCL2CYP3A4MAOALMNA | |
| Hydrochloric Acid SCHEMBL7823998 | 0.73 | BRD4 (0.41) | BRD4CCL2CYP3A4MAOALMNA | |
| SCHEMBL8041045 | 0.73 | BRD4 (0.41) | BRD4CCL2CYP3A4MAOALMNA | |
| SCHEMBL9016938 | 0.72 | BRD4 (0.40) | BRD4CCL2CYP3A4MAOALMNA | |
| SCHEMBL7826476 | 0.72 | BRD4 (0.40) | BRD4CCL2CYP3A4MAOALMNA | |
| SCHEMBL8041103 | 0.67 | BRD4 (0.36) | BRD4CCL2CYP3A4CA2 | |
| SCHEMBL18287893 | 0.66 | CYP3A4 (0.50) | BRD4CCL2CYP3A4MAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504232-A | Process for the preparation of an olefin polymer using specific metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |