Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017168 | 1.00 | PTPN1 (0.54) | PTPN1ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL8156416 | 0.80 | MEN1 (0.45) | PTPN1ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL23747110 | 0.80 | ALOX15 (0.68) | PTPN1ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL27414793 | 0.80 | ALOX15 (0.68) | PTPN1ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL9709450 | 0.79 | MEN1 (0.48) | PTPN1ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL16461955 | 0.78 | ALOX15 (0.42) | ALOX15 | |
| SCHEMBL16461953 | 0.78 | ALOX15 (0.42) | ALOX15 | |
| SCHEMBL9017160 | 0.77 | ALOX15 (0.59) | ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL22372389 | 0.77 | ALOX15 (0.59) | ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL22372388 | 0.77 | ALOX15 (0.59) | ALOX15MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414106-B1 | Process for the preparation of terpenes | EISAI CO LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5073659-A | Alkylation, Grignard reagent, zinc chloride catalyst and coppe r compound | EISAI CO., LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0414106-A2 | Process for the preparation of terpenes | Eisai Co., Ltd. (JP) | 1991-02-27 | — | — | EP | disclosed |