Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362989 | 0.84 | TSHR (0.38) | CA2 | |
| SCHEMBL28365491 | 0.81 | TSHR (0.36) | CA2 | |
| SCHEMBL27449069 | 0.81 | TSHR (0.36) | CA2 | |
| SCHEMBL1952006 | 0.81 | TSHR (0.36) | CA2 | |
| Ammonia Solution, Strong SCHEMBL11776045 | 0.81 | TSHR (0.36) | CA2 | |
| SCHEMBL2521502 | 0.81 | TSHR (0.36) | CA2 | |
| SCHEMBL28485977 | 0.81 | TSHR (0.36) | CA2 | |
| Ammonia Solution, Strong SCHEMBL27570613 | 0.81 | TSHR (0.36) | CA2 | |
| SCHEMBL11763685 | 0.81 | TSHR (0.36) | CA2 | |
| Tetrabuthylammonium SCHEMBL9017232 | 0.80 | SLC22A1 (0.39) | CYP1A2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537905-B1 | Water soluble derivatives of taxol with anti-neoplastic activity | VIRGINIA TECH INTELL PROP (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5352805-A | Reaction with a glycol; storage stability; antitumor, anticarcinogenic agents | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1994-10-04 | — | — | US | disclosed |
| US-5278324-A | Sulfonates | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0537905-A1 | Water soluble derivatives of taxol with anti-neoplastic activity | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0473326-A1 | Water soluble derivatives of taxol | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1992-03-04 | — | — | EP | disclosed |
| US-5059699-A | Antitumor agents; stability | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1991-10-22 | — | — | US | disclosed |