Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017197 | 0.80 | LMNA (0.36) | CA2CYP1A2 | |
| Monoethanolamine SCHEMBL5498813 | 0.79 | DGKA (0.46) | CA12CA2CA7CA9CA14 | |
| SCHEMBL9342617 | 0.79 | DGKA (0.52) | CA12CA2CA7CA9CA14 | |
| SCHEMBL339526 | 0.77 | DGKA (0.55) | CA12CA2CA7CA9CA14 | |
| SCHEMBL5431993 | 0.77 | DGKA (0.55) | CA12CA2CA7CA9CA14 | |
| SCHEMBL2464653 | 0.77 | DGKA (0.55) | CA12CA2CA7CA9CA14 | |
| SCHEMBL1827580 | 0.77 | DGKA (0.55) | CA12CA2CA7CA9CA14 | |
| SCHEMBL1445754 | 0.77 | DGKA (0.55) | CA12CA2CA7CA9CA14 | |
| SCHEMBL3846923 | 0.77 | DGKA (0.55) | CA12CA2CA7CA9CA14 | |
| SCHEMBL1593662 | 0.77 | DGKA (0.55) | CA12CA2CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537905-B1 | Water soluble derivatives of taxol with anti-neoplastic activity | VIRGINIA TECH INTELL PROP (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5352805-A | Reaction with a glycol; storage stability; antitumor, anticarcinogenic agents | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1994-10-04 | — | — | US | disclosed |
| US-5278324-A | Sulfonates | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1994-01-11 | — | — | US | disclosed |
| EP-0537905-A1 | Water soluble derivatives of taxol with anti-neoplastic activity | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0473326-A1 | Water soluble derivatives of taxol | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1992-03-04 | — | — | EP | disclosed |
| US-5059699-A | Antitumor agents; stability | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 1991-10-22 | — | — | US | disclosed |