Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 17/20 | 0.61 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155513 | 0.94 | PTGIR (0.69) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8858587 | 0.86 | PTGIR (0.72) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8414336 | 0.86 | PTGIR (0.49) | PTGIRTBXAS1 | |
| SCHEMBL9155480 | 0.85 | PTGIR (0.68) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9050868 | 0.84 | PTGIR (0.64) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9151307 | 0.81 | PTGIR (0.63) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL9017264 | 0.81 | PTGIR (0.63) | PTGIRTBXAS1PTGDR2 | |
| SCHEMBL8411209 | 0.80 | PTGIR (0.56) | PTGIRTBXAS1 | |
| SCHEMBL9050358 | 0.80 | PTGIR (0.43) | PTGIR | |
| SCHEMBL8811047 | 0.80 | ACHE (0.45) | PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5596009-A | TREATMENT OF THROMBOSIS, ATHERIOSCLEROSIS, ANTIISCHEMIC AGENTS, ANTIULCER AGENTS OR HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5389666-A | Administering for treatment and prevention of thrombosis, arteriosclerosis, ischemic heart diseases, gastric ulcer or hypertension | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |