Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 16/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017275 | 0.80 | PTGIR (0.60) | PTGIRPTGDR2PTGER1PTGER3PTGDR | |
| SCHEMBL9017321 | 0.79 | PTGIR (0.51) | PTGIRPTGDR2PTGER1PTGER3PTGDR | |
| SCHEMBL9017278 | 0.75 | PTGIR (0.60) | PTGIRPTGDR2PTGER1PTGER3PTGDR | |
| SCHEMBL9017294 | 0.75 | PTGIR (0.49) | PTGIRPTGDR2PTGER1PTGER3PTGDR | |
| SCHEMBL9269788 | 0.74 | PTGIR (0.51) | PTGIRPTGDR2PTGER1PTGER3PTGDR | |
| SCHEMBL7772442 | 0.73 | PTGIR (0.70) | PTGIRPTGDR2PTGER1PTGER3PTGDR | |
| SCHEMBL9017268 | 0.73 | PTGIR (0.57) | PTGIRPTGER1PTGER3PTGDRKDM4E | |
| SCHEMBL9017265 | 0.73 | PTGIR (0.57) | PTGIRPTGER1PTGER3PTGDRKDM4E | |
| SCHEMBL7777519 | 0.73 | PTGIR (0.57) | PTGIRPTGER1PTGER3PTGDRKDM4E | |
| SCHEMBL9267979 | 0.72 | PTGDR2 (0.49) | PTGIRPTGDR2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |