Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.57 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.57 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.57 |
| ▸ | CD69 | Q07108 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017268 | 1.00 | PTGIR (0.57) | PTGIRPTGER1PTGER3PTGDRCD69 | |
| SCHEMBL7777519 | 1.00 | PTGIR (0.57) | PTGIRPTGER1PTGER3PTGDRCD69 | |
| SCHEMBL7777521 | 0.84 | PTGIR (0.57) | PTGIRPTGER1PTGER3PTGDRCD69 | |
| SCHEMBL9017269 | 0.84 | PTGIR (0.57) | PTGIRPTGER1PTGER3PTGDRCD69 | |
| SCHEMBL9017274 | 0.84 | PTGIR (0.57) | PTGIRPTGER1PTGER3PTGDRCD69 | |
| SCHEMBL9017285 | 0.84 | PTGER1 (0.45) | PTGIRPTGER1PTGER3PTGDRRXRA | |
| SCHEMBL3479749 | 0.77 | RXRB (0.66) | PTGIRPTGER1PTGER3PTGDRCD69 | |
| SCHEMBL28548896 | 0.76 | RXRB (0.64) | PTGIRPTGER1PTGER3PTGDRCD69 | |
| SCHEMBL9017275 | 0.75 | PTGIR (0.60) | PTGIRPTGER1PTGER3PTGDRKDM4E | |
| SCHEMBL9017321 | 0.74 | PTGIR (0.51) | PTGIRPTGER1PTGER3PTGDRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |