Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779842 | 0.83 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1HIF1ATP53 | |
| SCHEMBL1686660 | 0.82 | TSHR (0.45) | ALDH1A1TSHRMAPK1HIF1ATP53 | |
| SCHEMBL7038816 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPK1HIF1ATP53 | |
| SCHEMBL11794978 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1HIF1ATP53 | |
| SCHEMBL2794253 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1HIF1ATP53 | |
| SCHEMBL1686731 | 0.77 | TSHR (0.45) | ALDH1A1TSHRMAPK1HIF1ATP53 | |
| SCHEMBL11199211 | 0.76 | MAPK1 (0.35) | ALDH1A1TSHRMAPK1HIF1ATP53 | |
| SCHEMBL11427785 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRHIF1A | |
| SCHEMBL30902237 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| SCHEMBL29991722 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPK1HIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8120117-A | — | — | None | — | — | JP | disclosed |
| JP-8119902-A | — | — | None | — | — | JP | disclosed |
| JP-H08119902-A | TRIBROMONEOPENTYL ALCOHOL DERIVATIVE | DAI ICHI KOGYO SEIYAKU CO LTD | 1996-05-14 | — | — | JP | disclosed |
| JP-H08120117-A | FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION | DAI ICHI KOGYO SEIYAKU CO LTD | 1996-05-14 | — | — | JP | disclosed |