Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734556 | 0.86 | GABRR1 (0.61) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL13700412 | 0.80 | GABRR1 (0.54) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL11663794 | 0.78 | GABRR1 (0.47) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL5139179 | 0.75 | GABRR1 (0.72) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL22166664 | 0.75 | ACE2 (0.53) | GABRR1CYP1A2BLMACE2 | |
| SCHEMBL22134234 | 0.75 | — | — | |
| SCHEMBL17017527 | 0.74 | GABRR1 (0.52) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL297723 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL27608648 | 0.73 | GABRR1 (0.56) | GABRR1CYP1A2BLMACE2LTA4H | |
| SCHEMBL5131552 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516869-A | Amino acid functionalized silicones and method for preparation | GENERAL ELECTRIC COMPANY (US) | 1996-05-14 | — | — | US | disclosed |
| US-5399653-A | Amino acid functionalized silicones and method for preparation | GENERAL ELECTRIC COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0594285-A2 | Amino acid functionalized silicones | GENERAL ELECTRIC COMPANY (US) | 1994-04-27 | — | — | EP | disclosed |
| US-5272241-A | Amino acid functionalized silicones and method for preparation | GENERAL ELECTRIC COMPANY (US) | 1993-12-21 | — | — | US | disclosed |