Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20734556 | 0.88 | GABRR1 (0.61) | GABRR1CYP1A2ACE2BLMLTA4H | |
| SCHEMBL15710642 | 0.81 | CHRM1 (0.39) | CYP1A2FOLH1CHRM1AKR1A1CHRM3 | |
| SCHEMBL22166664 | 0.81 | ACE2 (0.53) | GABRR1CYP1A2ACE2BLMTSHR | |
| SCHEMBL9017649 | 0.80 | GABRR1 (0.52) | GABRR1CYP1A2ACE2BLMLTA4H | |
| SCHEMBL6450939 | 0.79 | GABRR1 (0.33) | GABRR1CYP2C19MEN1GLAKMT2A | |
| SCHEMBL24770936 | 0.78 | CA1 (0.42) | GABRR1CYP1A2CYP2C19MEN1GLA | |
| SCHEMBL5139179 | 0.77 | GABRR1 (0.72) | GABRR1CYP1A2ACE2BLMLTA4H | |
| SCHEMBL24200475 | 0.77 | GAA (0.38) | CYP2C19MEN1KMT2A | |
| SCHEMBL22134234 | 0.76 | — | — | |
| SCHEMBL13259645 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10034869-B2 | S1P modulating agents | BIOGEN MA INC. (US) | 2018-07-31 | — | — | US | disclosed |
| US-20180028511-A1 | S1P MODULATING AGENTS | BIOGEN IDEC MA | 2018-02-01 | — | — | US | disclosed |
| US-9808449-B2 | S1P modulating agents | BIOGEN MA INC. (US) | 2017-11-07 | — | — | US | disclosed |
| WO-2009117409-A2 | A HIGH THROUGHPUT PROTEIN INTERACTION ASSAY | MERCK & CO., INC. (US) | 2009-09-24 | — | — | WO | disclosed |
| WO-2007088996-A1 | TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10034869-B2 | S1P modulating agents | S1PR2, S1PR1, S1PR3 | GABRR1 400/4885CYP1A2 2926/4885ACE2 3038/4885 |
| US-20180028511-A1 | S1P MODULATING AGENTS | S1PR2, S1PR1, S1PR3 | GABRR1 188/4885CYP1A2 2647/4885ACE2 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.