SCHEMBL9017771

SCHEMBL9017771

C1CN2CCN1CC2.Nc1nc(N)nc(N)n1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.36
HRH4 Q9H3N8 5/20 0.33
LMNA P02545 1/20 0.33
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
CYP2C19 P33261 1/20 0.32
POLB P06746 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32
ADORA1 P30542 1/20 0.32
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8356506 0.76 CASP1 (0.50) CASP1LMNASMN1; SMN2POLBADORA3
SCHEMBL29876207 0.76
SCHEMBL29900242 0.76
SCHEMBL175612 0.76 CASP1 (0.50) CASP1LMNASMN1; SMN2POLBADORA3
SCHEMBL29485005 0.76
SCHEMBL8465809 0.76 CASP1 (0.50) CASP1LMNASMN1; SMN2POLBADORA3
SCHEMBL25853 0.76
SCHEMBL9579151 0.76 CASP1 (0.50) CASP1LMNASMN1; SMN2POLBADORA3
SCHEMBL9583239 0.76 CASP1 (0.50) CASP1LMNASMN1; SMN2POLBADORA3
Cyclohexane SCHEMBL9718392 0.72 CASP1 (0.42) CASP1LMNACRHBPCRHR2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5554691-A REACTING MONOHYDROXYLATED CONJUGATED DIENE POLYMER WITH DIISOCYANATE OR MULTIFUNCTIONAL ISOCYANATE, REACTING THE PRODUCT WITH AN EPOXY RESIN OR ACRYLIC RESIN HAVING HYDROXYL GROUPS SHELL OIL COMPANY (US) 1996-09-10 US disclosed
US-5378761-A Polymer coating with epoxy resins SHELL OIL COMPANY (US) 1995-01-03 US disclosed