Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104361 | 0.79 | POLB (0.48) | PDE10ATSHRCASP1TP53TDP1 | |
| SCHEMBL31634585 | 0.77 | PDE10A (0.54) | PDE10ATSHRCASP1TP53TDP1 | |
| SCHEMBL4968725 | 0.77 | PDE10A (0.54) | PDE10ATSHRCASP1TP53TDP1 | |
| SCHEMBL3517813 | 0.75 | EP300 (0.41) | TSHRTDP1POLBHSD17B10ALDH1A1 | |
| SCHEMBL28193310 | 0.75 | POLB (0.44) | TSHRCASP1TP53TDP1POLB | |
| SCHEMBL10512501 | 0.75 | TRPA1 (0.44) | PDE10ATSHRCASP1TP53TDP1 | |
| SCHEMBL3080081 | 0.75 | POLB (0.44) | PDE10ATSHRCASP1TP53TDP1 | |
| SCHEMBL30962921 | 0.75 | POLB (0.56) | PDE10ATSHRCASP1TP53TDP1 | |
| SCHEMBL31495833 | 0.75 | PDE10A (0.52) | PDE10ATSHRCASP1TP53TDP1 | |
| SCHEMBL1233639 | 0.75 | POLB (0.56) | PDE10ATSHRCASP1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591060-B1 | 4-Substituted meta amino phenols, process for their preparation their use in dyeing keratinic fibres and intermediates used in their preparation | OREAL (FR) | 1996-12-18 | — | — | EP | disclosed |
| EP-0591060-A1 | 4-Substituted meta amino phenols, process for their preparation their use in dyeing keratinic fibres and intermediates used in their preparation | L'OREAL (FR) | 1994-04-06 | — | — | EP | disclosed |