Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | CYP11A1 | P05108 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135217 | 0.85 | CYP19A1 (0.73) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL9634038 | 0.83 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL11840135 | 0.83 | CYP19A1 (0.71) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL11841553 | 0.83 | CYP19A1 (0.71) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL20135247 | 0.80 | CYP19A1 (0.66) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL14466635 | 0.70 | CYP19A1 (0.52) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| SCHEMBL16509358 | 0.69 | CYP19A1 (0.75) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| Rogletimide SCHEMBL4281 | 0.68 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| Rogletimide SCHEMBL9372682 | 0.68 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 | |
| Aminoglutethimide SCHEMBL7728932 | 0.68 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP17A1CYP11A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599886-A4 | MACROMONOMERS HAVING REACTIVE END GROUPS. | MAXDEM INC (US) | 1996-07-24 | — | — | EP | disclosed |
| EP-0599886-A1 | MACROMONOMERS HAVING REACTIVE END GROUPS | MAXDEM INCORPORATED (US) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993004099-A1 | MACROMONOMERS HAVING REACTIVE END GROUPS | MAXDEM INCORPORATED (US) | 1993-03-04 | — | — | WO | disclosed |