Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KDM6B | O15054 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413722 | 0.86 | KDM4C (0.46) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL14357917 | 0.83 | HDAC1 (0.46) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL29373586 | 0.81 | HDAC1 (0.45) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL5749683 | 0.81 | HDAC1 (0.45) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL14439746 | 0.81 | KDM4D (0.68) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL6988265 | 0.81 | CYP1A2 (0.41) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL23463919 | 0.80 | HDAC1 (0.56) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL15432248 | 0.80 | KDM4E (0.51) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL27684513 | 0.79 | SIRT3 (0.55) | KDM4CALDH1A1KDM4DMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL9426022 | 0.79 | CYP1A2 (0.40) | HDAC1HDAC2HDAC3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477903-B1 | Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-04-03 | — | — | EP | disclosed |