Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.68 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23463919 | 0.90 | HDAC1 (0.56) | KDM4DKDM4CHDAC1HDAC2HDAC3 | |
| SCHEMBL10644415 | 0.87 | HDAC2 (0.66) | KDM4DKDM4CHDAC1HDAC2HDAC3 | |
| SCHEMBL13740469 | 0.82 | KDM4D (0.65) | KDM4DKDM4CHDAC1HDAC2HDAC3 | |
| SCHEMBL28561950 | 0.82 | KDM4D (0.69) | KDM4DKDM4CHDAC1HDAC2HDAC3 | |
| SCHEMBL31261245 | 0.82 | RAB9A (0.58) | HDAC1HDAC2HDAC3NAMPTHTT | |
| SCHEMBL22441103 | 0.82 | RAB9A (0.58) | HDAC1HDAC2HDAC3NAMPTHTT | |
| SCHEMBL9017891 | 0.81 | HDAC1 (0.49) | KDM4DKDM4CHDAC1HDAC2HDAC3 | |
| SCHEMBL5571924 | 0.81 | HDAC1 (0.66) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL30599581 | 0.81 | KDM4D (0.68) | KDM4DKDM4CHDAC1HDAC2HDAC3 | |
| SCHEMBL12320459 | 0.81 | KDM4D (0.68) | KDM4DKDM4CHDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256287-B2 | Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2007-08-14 | — | — | US | disclosed |
| US-7256287-B2 | Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2007-08-14 | — | — | US | disclosed |