Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018256 | 0.94 | KMT2A (0.52) | KMT2AMEN1P4HTMMAPTALDH1A1 | |
| SCHEMBL9018091 | 0.92 | MEN1 (0.44) | KMT2AMEN1P4HTMMAPTLMNA | |
| SCHEMBL9018427 | 0.92 | CA1 (0.53) | KMT2AMEN1P4HTMMAPTALDH1A1 | |
| SCHEMBL9018100 | 0.91 | PPARA (0.47) | KMT2AMEN1MAPTLMNARAB9A | |
| SCHEMBL9018167 | 0.91 | MAPT (0.48) | KMT2AMEN1MAPTLMNARAB9A | |
| SCHEMBL9018271 | 0.91 | PPARA (0.47) | KMT2AMEN1MAPTLMNARAB9A | |
| SCHEMBL9018513 | 0.91 | NPC1 (0.47) | KMT2AMEN1P4HTMMAPTLMNA | |
| SCHEMBL9018057 | 0.91 | KMT2A (0.58) | KMT2AMEN1P4HTMMAPTALDH1A1 | |
| SCHEMBL9018037 | 0.90 | KMT2A (0.53) | KMT2AMEN1P4HTMMAPTALDH1A1 | |
| SCHEMBL9018054 | 0.90 | ACACB (0.43) | KMT2AMEN1P4HTMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590520-B1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AG (DE) | 1996-06-12 | — | — | EP | disclosed |
| EP-0590520-A1 | Acylsulphonamido and sulphonamidopyridine-2-carboxylic acid esters, pyridine-n-oxides thereof, a process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | disclosed |