Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921316 | 0.85 | ECE1 (0.41) | MMEECE1AGTR2 | |
| SCHEMBL8923644 | 0.83 | ECE1 (0.44) | ACACBPOLBRAB9ANPC1NR1H4 | |
| SCHEMBL8923661 | 0.83 | ECE1 (0.44) | ACACBPOLBRAB9ANPC1NR1H4 | |
| SCHEMBL8921341 | 0.83 | ECE1 (0.49) | MMEECE1AGTR2 | |
| SCHEMBL8922286 | 0.80 | MME (0.42) | XDHMMEECE1AGTR2 | |
| SCHEMBL8922640 | 0.78 | MME (0.41) | XDHMMEECE1AGTR2 | |
| SCHEMBL8920411 | 0.74 | ROCK2 (0.38) | MMEECE1AGTR2 | |
| SCHEMBL12481327 | 0.74 | MME (0.43) | MMEECE1AGTR2 | |
| SCHEMBL8920292 | 0.69 | ECE1 (0.35) | POLBGAAMMEECE1AGTR2 | |
| SCHEMBL7150536 | 0.65 | SLC6A4 (0.37) | ACACBCYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550119-A | ENDOTHELIN-CONVERTING ENZYM INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1996-08-27 | — | — | US | disclosed |