Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 3/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.66 |
| ▸ | RORC | P51449 | 1/20 | 0.66 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.66 |
| ▸ | POLA1 | P09884 | 1/20 | 0.64 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.57 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.56 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10825219 | 0.93 | GRIN1 (0.66) | OSBPUSP2CYP46A1LMNAABCB1 | |
| SCHEMBL9394607 | 0.91 | USP2 (0.57) | OSBPUSP2CYP46A1LMNAABCB1 | |
| SCHEMBL10930823 | 0.90 | USP2 (0.65) | OSBPUSP2CYP46A1LMNAABCB1 | |
| SCHEMBL10929495 | 0.90 | USP2 (0.65) | OSBPUSP2CYP46A1LMNAABCB1 | |
| SCHEMBL10929500 | 0.90 | USP2 (0.65) | OSBPUSP2CYP46A1LMNAABCB1 | |
| SCHEMBL11674771 | 0.87 | POLA1 (0.68) | OSBPUSP2CYP46A1LMNAABCB1 | |
| SCHEMBL27584885 | 0.86 | OSBP (0.59) | OSBPUSP2CYP46A1LMNAABCB1 | |
| SCHEMBL27963054 | 0.86 | USP2 (0.68) | OSBPUSP2CYP46A1LMNAABCB1 | |
| SCHEMBL6060845 | 0.86 | USP2 (0.68) | OSBPUSP2CYP46A1LMNAABCB1 | |
| SCHEMBL27963051 | 0.86 | USP2 (0.68) | OSBPUSP2CYP46A1LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749437-A1 | STEROID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR PHARMACEUTICAL USES | MAGAININ PHARMACEUTICALS INC. (US) | 1996-12-27 | — | — | EP | disclosed |
| EP-0688333-A1 | STEROID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE AS ANTIBIOTICS OR DISINFECTANTS | MAGAININ PHARMACEUTICALS INC. (US) | 1995-12-27 | — | — | EP | disclosed |
| WO-1995024415-A1 | STEROID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR PHARMACEUTICAL USES | MAGAININ PHARMACEUTICALS INC. (US) | 1995-09-14 | — | — | WO | disclosed |
| WO-1994020520-A1 | STEROID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE AS ANTIBIOTICS OR DISINFECTANTS | MAGAININ PHARMACEUTICALS INC. (US) | 1994-09-15 | — | — | WO | disclosed |