SCHEMBL10929495

SCHEMBL10929495

CC(=O)O[C@@]1(O)CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC[C@H]([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@@H]32)C1

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.65
CYP46A1 Q9Y6A2 2/20 0.65
LMNA P02545 1/20 0.65
ABCB1 P08183 1/20 0.65
OSBP P22059 1/20 0.65
RORC P51449 1/20 0.65
OSBP2 Q969R2 1/20 0.65
POLA1 P09884 1/20 0.63
GRIN1 Q05586 12/20 0.60
GRIN2B Q13224 12/20 0.60
GRIN2A Q12879 10/20 0.59
SRD5A1 P18405 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10929500 1.00 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL10930823 1.00 USP2 (0.65) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL9018738 0.90 OSBP (0.66) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL7741660 0.90 USP2 (0.70) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL4284415 0.89 USP2 (0.69) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL1243707 0.89 USP2 (0.66) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL4654756 0.88 USP2 (0.59) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL3508152 0.87 CYP46A1 (0.71) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL6060845 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP
SCHEMBL27963051 0.87 USP2 (0.68) USP2CYP46A1LMNAABCB1OSBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60163898-A None JP disclosed
JP-60139698-A None JP disclosed
JP-S60163898-A PROCESS FOR SELECTIVE SCISSION BETWEEN 24 AND 25 SITE OF STEROL SHOWA DENKO KK 1985-08-26 JP disclosed
JP-S60139698-A 3BETA-ACETOXY-7-OXO-24-TRIFLUOROACETYLOXO-DELTA5-CHOLENE SHOWA DENKO KK 1985-07-24 JP disclosed