SCHEMBL9018876

SCHEMBL9018876

O=C(O)c1ccc(SC(Cl)(Cl)Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
TP53 P04637 1/20 0.52
ALOX15 P16050 1/20 0.48
SRD5A2 P31213 5/20 0.46
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA12 O43570 1/20 0.44
CA3 P07451 1/20 0.44
TYR P14679 1/20 0.44
DRD1 P21728 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
ALDH1A1 P00352 2/20 0.43
TPMT P51580 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8488706 0.91 TSHR (0.43) TSHRTP53ALOX15SRD5A2CA1
SCHEMBL10407691 0.85 TSHR (0.50) TSHRTP53ALOX15SRD5A2CA1
SCHEMBL15006816 0.84 SRD5A2 (0.42) SRD5A2ALDH1A1HTT
SCHEMBL15007037 0.82 ALDH1A1 (0.54) TSHRSRD5A2ALDH1A1HTTCES2
SCHEMBL1015553 0.78 KCNK2 (0.57) TSHRTP53SRD5A2ALDH1A1HTT
SCHEMBL735343 0.78 TSHR (0.52) TSHRTP53ALOX15SRD5A2CA1
SCHEMBL8779804 0.78 KDM4E (0.38) ALDH1A1
SCHEMBL15006775 0.78 SRD5A2 (0.53) TSHRALOX15SRD5A2CA1CA2
Terephthalic Acid SCHEMBL1243625 0.75 TSHR (0.80) TSHRTP53ALOX15SRD5A2CA1
SCHEMBL2821868 0.75 TP53 (0.48) TSHRTP53SRD5A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102924352-B Method for synthesizing 4-mercaptobenzoate BEIJING INSIGHT HIGH TECHNOLOGY CO LTD 2013-11-20 CN disclosed
CN-102924352-A Method for synthesizing 4-mercaptobenzoate BEIJING INSIGHT HIGH TECHNOLOGY CO LTD 2013-02-13 CN disclosed
EP-0742201-A1 PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-11-13 EP disclosed