Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.57 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7234994 | 0.99 | ALOX5 (0.70) | ALOX5HDAC6 | |
| SCHEMBL8799865 | 0.87 | ALOX5 (0.73) | ALOX5HDAC6 | |
| SCHEMBL10521151 | 0.86 | ALOX5 (0.69) | ALOX5HDAC6 | |
| SCHEMBL8801108 | 0.86 | ALOX5 (0.69) | ALOX5HDAC6 | |
| SCHEMBL8800680 | 0.85 | ALOX5 (0.67) | ALOX5HDAC6 | |
| SCHEMBL8801130 | 0.85 | ALOX5 (0.67) | ALOX5HDAC6 | |
| SCHEMBL8965421 | 0.85 | ALOX5 (0.73) | ALOX5HDAC6 | |
| SCHEMBL10520188 | 0.85 | ALOX5 (0.70) | ALOX5HDAC6 | |
| SCHEMBL8965314 | 0.84 | ALOX5 (0.66) | ALOX5HDAC6 | |
| SCHEMBL8965126 | 0.84 | ALOX5 (0.70) | ALOX5HDAC6CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414019-B1 | Subsituted N-(quinolin-2-yl-methoxy)benzylsulfonylureas | BAYER AG (DE) | 1996-05-29 | — | — | EP | disclosed |
| US-5179106-A | SUBSTITUTED N-(QUINOLIN-2-YL-METHOXY) BENZYL-SULPHONYLUREA LEUKOTRIENE SYNTHESIS INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-12 | — | — | US | disclosed |