Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 2/20 | 0.41 |
| ▸ | EIF4E | P06730 | 6/20 | 0.40 |
| ▸ | KMO | O15229 | 4/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | PPP1CA | P62136 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702708 | 0.82 | RPA1 (0.44) | RPA1EIF4EKMOPPP1CANOTUM | |
| SCHEMBL9019127 | 0.69 | MAOB (0.43) | KMO | |
| SCHEMBL9019069 | 0.66 | ALDH1A1 (0.46) | — | |
| SCHEMBL9019068 | 0.64 | MAPT (0.38) | KMO | |
| SCHEMBL9019037 | 0.64 | NPC1 (0.42) | RPA1PPP1CANOTUM | |
| SCHEMBL9316754 | 0.63 | AHR (0.38) | RPA1EIF4EKMONOTUM | |
| SCHEMBL9019071 | 0.62 | MAOB (0.39) | KMO | |
| SCHEMBL10834339 | 0.62 | RPA1 (0.49) | RPA1NOTUM | |
| SCHEMBL2225438 | 0.62 | ALDH1A1 (0.57) | RPA1EIF4EAKR1C2AKR1C1 | |
| SCHEMBL2637495 | 0.61 | TSHR (0.69) | RPA1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434940-B1 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID CO (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5399716-A | N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5347016-A | N-oxygenated arylpyrrole intermediates for insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| US-5232979-A | Insecticides, miticides, nematocides | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0434940-A2 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |