Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124420 | 0.77 | POLB (0.54) | POLBCYP2C9CYP2C19L3MBTL1KMT2A | |
| SCHEMBL19642630 | 0.76 | GSK3B (0.61) | POLBCYP2C9CYP2C19L3MBTL1KMT2A | |
| SCHEMBL928740 | 0.74 | PDPK1 (0.47) | POLBL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL9019162 | 0.74 | L3MBTL1 (0.48) | POLBCYP2C9CYP2C19L3MBTL1KMT2A | |
| SCHEMBL25612575 | 0.74 | USP2 (0.58) | L3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL19660192 | 0.73 | L3MBTL1 (0.61) | POLBCYP2C9CYP2C19L3MBTL1KMT2A | |
| SCHEMBL2672622 | 0.72 | PPARG (0.47) | CYP2C9CYP2C19MAPT | |
| SCHEMBL8306301 | 0.72 | POLB (0.64) | POLBCYP2C9CYP2C19L3MBTL1KMT2A | |
| SCHEMBL28802831 | 0.71 | L3MBTL1 (0.54) | POLBCYP2C9CYP2C19L3MBTL1KMT2A | |
| SCHEMBL1155256 | 0.71 | POLB (0.44) | POLBCYP2C9CYP2C19L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434940-B1 | N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents | AMERICAN CYANAMID CO (US) | 1996-05-29 | — | — | EP | disclosed |