Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 6/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.39 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.39 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1525888 | 0.79 | TTR (0.78) | TTRNSD2AURKAAURKBIDO1 | |
| SCHEMBL29516385 | 0.79 | TTR (0.78) | TTRNSD2AURKAAURKBIDO1 | |
| SCHEMBL150853 | 0.79 | TTR (0.78) | TTRNSD2AURKAAURKBIDO1 | |
| SCHEMBL9649777 | 0.77 | TTR (0.75) | TTRNSD2AURKAAURKBIDO1 | |
| SCHEMBL2093553 | 0.77 | TTR (0.75) | TTRNSD2AURKAAURKBIDO1 | |
| SCHEMBL2093558 | 0.77 | TTR (0.75) | TTRNSD2AURKAAURKBIDO1 | |
| SCHEMBL108422 | 0.76 | LDHA (0.64) | TTRNSD2AURKAAURKBIDO1 | |
| SCHEMBL1377189 | 0.76 | GAA (0.58) | TTRNSD2ALDH1A1CYP3A4TSHR | |
| SCHEMBL11241011 | 0.76 | TTR (0.41) | TTRNSD2AURKAAURKBIDO1 | |
| Nitrogen SCHEMBL28283073 | 0.76 | TTR (0.72) | TTRNSD2AURKAAURKBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017095924-A1 | LIVER-TARGETED PRODRUG COMPOSITIONS AND METHODS OF USING THE SAME | GEORGETOWN UNIVERSITY (US) | 2017-06-08 | — | — | WO | disclosed |
| EP-0650595-A4 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF. | PATCHORNIK ZIPORA (IL) | 1996-08-21 | — | — | EP | disclosed |
| EP-0650595-A1 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF | PATCHORNIK, Zipora (IL) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994001771-A1 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF | PATCHORNIK, ZIPORA (IL) | 1994-01-20 | — | — | WO | disclosed |