Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019372 | 0.83 | KMT2A (0.56) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL28372434 | 0.82 | ALDH1A1 (0.57) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL9644494 | 0.78 | KMT2A (0.53) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL9644201 | 0.78 | KMT2A (0.57) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL20069629 | 0.78 | KMT2A (0.50) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL31697577 | 0.78 | ALDH1A1 (0.56) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL13333018 | 0.77 | TSHR (0.62) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL31129249 | 0.77 | KMT2A (0.67) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL10404298 | 0.77 | KMT2A (0.67) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL3761569 | 0.77 | KMT2A (0.68) | KMT2AMEN1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436348-B1 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LTD (GB) | 1996-11-13 | — | — | EP | disclosed |
| US-5126338-A | FUNGICIDES WHICH ARE N-PYRIDYL-CYCLOPROPANE CARBOXAMIDES OR DERIVATIVES THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-30 | — | — | US | disclosed |
| EP-0436348-A2 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LIMITED (GB) | 1991-07-10 | — | — | EP | disclosed |