SCHEMBL9019386

SCHEMBL9019386

CC1(OC=O)CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28791801 0.83
SCHEMBL9643382 0.80
SCHEMBL2077030 0.74
SCHEMBL6714704 0.74
SCHEMBL28100808 0.72
SCHEMBL9418544 0.65
SCHEMBL10442074 0.64
SCHEMBL569018 0.63
SCHEMBL1140316 0.63
SCHEMBL30601954 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107814798-B 3-substituted acrylic acid compound and preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2020-11-03 CN disclosed
EP-0436348-B1 Pyridyl cyclopropane derivatives with fungicidal activity ZENECA LTD (GB) 1996-11-13 EP disclosed
US-5126338-A FUNGICIDES WHICH ARE N-PYRIDYL-CYCLOPROPANE CARBOXAMIDES OR DERIVATIVES THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-30 US disclosed
US-5047415-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0436348-A2 Pyridyl cyclopropane derivatives with fungicidal activity ZENECA LIMITED (GB) 1991-07-10 EP disclosed