SCHEMBL9019552

SCHEMBL9019552

CCCCCCCC(=S)CCCCO

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.65
ALDH1A1 P00352 4/20 0.65
LMNA P02545 2/20 0.65
HSD17B10 Q99714 2/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
SMN1; SMN2 Q16637 1/20 0.60
CES2 O00748 3/20 0.44
CES1 P23141 3/20 0.44
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 6/20 0.42
PPARD Q03181 6/20 0.42
PPARA Q07869 6/20 0.42
HDAC11 Q96DB2 5/20 0.42
TLR2 O60603 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
FABP4 P15090 2/20 0.42
PTPN1 P18031 2/20 0.42
SLC22A6 Q4U2R8 1/20 0.42
SLC22A8 Q8TCC7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295270 0.90 TSHR (0.50) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL4490108 0.90 TSHR (0.50) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL295049 0.90 TSHR (0.50) TSHRALDH1A1LMNAHSD17B10MEN1
SCHEMBL1123351 0.89 CES2 (0.52) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL11776994 0.89 CES2 (0.52) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL11776999 0.89 CES2 (0.52) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9445402 0.89 CES2 (0.52) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1123690 0.87 CES2 (0.50) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL7543307 0.87 CES2 (0.50) TSHRALDH1A1HSD17B10MEN1KMT2A
SCHEMBL24338481 0.84 CES2 (0.48) TSHRALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0573142-B1 Pressure-sensitive adhesives ROHM & HAAS (US) 1996-02-14 EP disclosed
US-5435879-A Improved cohesive strength ROHM AND HAAS COMPANY (US) 1995-07-25 US disclosed
EP-0357287-B1 Extended polymer compositions and textile materials manufactured therewith ROHM & HAAS (US) 1994-11-17 EP disclosed
US-5362816-A Reacted with ammonia to form an enamine group ROHM AND HAAS COMPANY (US) 1994-11-08 US disclosed
US-5283277-A A mixture of latex polymer having pendent carbonyl or nitrile groups and a chalcogenide, e.g. urea, thiourea; paints; textile binders having good wet and dry tensile strength ROHM AND HAAS COMPANY (US) 1994-02-01 US disclosed
EP-0407667-B1 Pressure-sensitive adhesives and manufactured articles ROHM & HAAS (US) 1994-01-05 EP disclosed
US-5270121-A Polymer-coated articles ROHM AND HAAS COMPANY (US) 1993-12-14 US disclosed
EP-0573142-A1 Pressure-sensitive adhesives ROHM AND HAAS COMPANY (US) 1993-12-08 EP disclosed
US-5264475-A Extended polymer compositions and textile materials manufactured therewith ROHM AND HAAS COMPANY (US) 1993-11-23 US disclosed
EP-0241127-B1 TEXTILE MATERIALS, METHODS OF MANUFACTURE AND COMPOSITIONS FOR USE THEREIN ROHM AND HAAS COMPANY (US) 1993-10-13 EP disclosed
EP-0358313-A1 Method for producing an article containing a radiation cross-linked polymer and the article produced thereby ROHM AND HAAS COMPANY (US) 1990-03-14 EP disclosed
US-4908229-A Contacting substrate with unsaturated ester polymer containing pendant functional groups, curing with radiation UNION OIL OF CALIFORNIA (US) 1990-03-13 US disclosed
US-4908403-A High cohesive strength UNION OIL OF CALIFORNIA (US) 1990-03-13 US disclosed
EP-0357287-A1 Extended polymer compositions and textile materials manufactured therewith ROHM AND HAAS COMPANY (US) 1990-03-07 EP disclosed
US-4900615-A Textile materials and compositions for use therein UNION OIL COMPANY OF CALIFORNIA (US) 1990-02-13 US disclosed
US-4855349-A Mastic and caulking compositions and composite articles UNION OIL COMPANY OF CALIFORNIA (US) 1989-08-08 US disclosed
EP-0296286-A1 Pressure sensitive adhesives and adhesive articles UNION OIL COMPANY OF CALIFORNIA (US) 1988-12-28 EP disclosed
US-4759983-A Conjugated diolefin polymer, olefin ester interpolymers, olefinically unsaturated carboxylic acid ester polymer, alkenyl ether polymer and combinations UNION OIL COMPANY OF CALIFORNIA (US) 1988-07-26 US disclosed
EP-0258988-A2 Mastic and caulking compositions and composite articles ROHM AND HAAS COMPANY (US) 1988-03-09 EP disclosed
EP-0244997-A2 Pressure sensitive adhesives and manufactured articles UNION OIL COMPANY OF CALIFORNIA (US) 1987-11-11 EP disclosed